Need for Vaccination for VL Elimination

Submit Manuscript | http://medcraveonline.com rash which is on the rise. Clinical symptoms of VL disease in the initial infective stages overlap with symptoms of other diseases that make it difficult to diagnose. The VL disease is still a major health challenge in parts of the developing world having people in the most impoverished conditions where the disease is endemic. VL is caused by parasite Leishmania donovani and is spread by female Phlebotomine Sand fly (Phlebotomus argentipes) which is the vector transmitting the disease to humans. In VL the parasite infects the mononuclear phagocytic system affecting spleen, liver and bone marrow. Chemotherapy and vector control are the main stay of management and control respectively for VL in the current existing programs. No effective vaccine for VL is available as yet. The efforts for Kala Azar management have increased and the major strategies included the following.